Measurements of Crosslinked Fibrin Degradation Products
نویسندگان
چکیده
منابع مشابه
Fibrinogen-fibrin degradation products.
The identification of the molecular structure of fibrinogen has given a better understanding of many clinical conditions associated with abnormalities of fibrinogen. Proteolysis of fibrinogen or fibrin by its natural lytic enzyme, plasmin, leads to the formation of degradation products which are of great importance in the laboratory diagnosis of many pathological conditions. The biochemical and...
متن کاملSpecific identification of fibrin polymers, fibrinogen degradation products, and crosslinked fibrin degradation products in plasma and serum with a new sensitive technique.
A new method is described for identifying low concentrations of circulating derivatives of fibrinogen and fibrin, even when present in heterogeneous mixtures. This technique is applicable to plasma and serum and uses electrophoresis in 2% agarose in the presence of sodium dodecyl sulfate (SDS) followed by immunological identification of separated derivatives, using radiolabeled antifibrinogen a...
متن کاملFibrin degradation products in rheumatoid arthritis.
The presence of fibrin in the joints, raised levels of blood fibrinogen, and an increased total daily fibrinogen turnover are well-known features of rheumatoid arthritis (Takeda, 1967) and inflammatory arthritis. A possible role for fibrin in the pathogenesis of rheumatoid arthritis, through its action as an autoimmunogen, was suggested by the production of a chronic inflammatory arthritis in r...
متن کاملFibrin-fibrinogen degradation products in cerebrospinal fluid.
An increase in low molecular weight fibrin-fibrinogen degradation products (FDP) was demonstrated in cerebrospinal fluid (CSF) from 17 of 18 patients with bacterial or viral meningitis compared with 29 patients without meningitis. The CSF also showed an increase in coagulation proteins of molecular weight less than 90000 (factors VII, IX, and plasminogen) but did not contain fibrinogen (MW 3400...
متن کاملMenstrual blood loss and fibrin degradation products.
As part of a large-scale study of menstrual blood loss in the community serum fibrin degradation products were measured soon after menstruation in 331 women. No significant correlation was found between the amount of blood lost and the serum level of fibrin degradation products. These findings conflict with reports suggesting that excessive intrauterine fibrinolysis, which may play a part in me...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 1991
ISSN: 1880-8808,0915-7441
DOI: 10.2491/jjsth.2.82